National Centers for Systems Biology

Past Centers

Center for Cell Dynamics

Principal investigator: Garrett M. Odell, Ph.D., University of Washington Friday Harbor Laboratories
Center for Cell Dynamics website

The Center for Cell Dynamics focused both on high-resolution imaging methods for visualizing molecular interactions and on building computer simulations that capture systems-level properties of pattern formation, cytoskeleton dynamics, and cell cycle regulation in worms, flies, and marine invertebrates.

Center for Modeling Integrated Metabolic Systems

Principal investigator: Gerald M. Saidel, Ph.D., Case Western Reserve University
Center for Modeling Integrated Metabolic Systems website

The Center for Modeling Integrated Metabolic Systems focused on quantifying relationships between cellular metabolism and physiological responses of tissue-organ systems and the whole body. Primary emphasis was on cellular metabolism in skeletal muscle, the brain, the heart, and the liver to evaluate metabolic pathways and regulatory mechanisms under normal and abnormal states.